The InviMag® Free Circulating DNA Kit/ IG enables efficient, fully automated purification of cell-free circulating DNA (cfDNA) fragments from 4 ml of plasma samples on the InviGenius® PLUS instrument. During the purification process the sample is up concentrated to a final elution volume of 40 µl.
The InviGenius® PLUS simplifies laboratory workflows providing a fully automated, walk-away sample purification. The instrument allows kit chemistry and samples to be tracked using barcodes. All protocols are available pre-programmed and are suitable for use with Invitek extraction kits.
Specifications | |
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Downstream application | PCR techniques, NGS, hybridization methods and methylation analysis |
Target nucleic acid | Cell-free circulating DNA (cfDNA, ctDNA) |
Starting material | Up to 4000 µl serum or plasma (from blood stabilized in EDTA or citrate, but not heparin) |
Yield | 1 - 100 ng/ml plasma depending on sample (storage and source) |
Quality | Depending on sample type |
Preparation time | For 12 samples approx. 160 min (MT protocol), 190 min (AT protocol) |
Elution Volume | 40 µl |
Technology | Magnetic beads |
Certification | CE-IVD (in compliance with REGULATION (EU) 2017/746 on in vitro diagnostic medical devices) |
Product Name | Package Size | Catalogue No. |
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InviMag® Free Circulating DNA Kit/ IG | 8 x 12 purifications | 2439320400 |
The kit is intended to be used for serum/plasma samples. However, research experiments have shown that it is also possible to extract cfDNA from urine samples.
Elution Buffer M: 10 mM Tris pH 8.5 – 9