Our oligos are produced in GMP-compliant cleanroom environment according to the customer specifications and with quick turnaround times. All oligos are verified by electrospray ionization mass spectrometry (ESI-MS) prior to shipping ensuring the quality and high coupling efficiency of every synthesis. We offer a wide range of modifications and different synthesis scales ranging from 25 nmol to 1 µmol, with variable degrees of purification depending on the application – standard desalting quality to RP-HPLC purified oligos.
| Scale | Length (Bases) | Yield | Purification |
|---|---|---|---|
| 10 nmol | 15–35 | ≥ 5 nmol | Desalting |
| 25 nmol | 15–60 | ≥ 12 nmol / ≥ 6 nmol | Desalting / HPLC |
| 50 nmol | 12–90 | ≥ 20 nmol / ≥ 10 nmol | Desalting / HPLC |
| 100 nmol | 10–90 | ≥ 35 nmol / ≥ 20 nmol | Desalting / HPLC |
| 200 nmol | 6–100 | ≥ 50 nmol / ≥ 30 nmol | Desalting / HPLC |
| 1 µmol | 6–199 | ≥ 150 nmol / ≥ 90 nmol | Desalting / HPLC |
List of available modifications.
| Category | Examples | Notes |
|---|---|---|
| 5' Fluorophores | FAM / HEX / CalFluor Red 610 / Cy5 / Cy3 / JOE / VIC / ROX (NH ESTER) / Cy5 (NH ESTER) | — |
| 5' Modifications | Biotin / Amino / Phosphorylation | — |
| 3' Modifications | BHQ1 / BHQ2 / BHQ3 / TAMRA / SPACER C3 / SPACER C9 / SPACER C18 / MGB | — |
| Backbone | Inosine / LNA Bases / O-Methyl Bases / Phosphorothioate Bond (PTO) | — |
List of supported quenchers.
| Quencher | Compatibility (Fluorophores) |
|---|---|
| BHQ1 | FAM / HEX / JOE / VIC / Cy3 |
| BHQ2 | HEX / JOE / VIC / Cy3 / Cy5 / CalFluor Red 610 / ROX (NH ESTER) / Cy5 (NH ESTER) |
| BHQ3 | Cy5 |
| TAMRA | FAM / HEX / JOE / VIC |
| MGB | FAM / HEX / JOE / VIC / Cy3 / Cy5 |
Recommended dye alternatives by base fluorophore.
| Base Fluorophore | Alternatives |
|---|---|
| FAM | ATTO 465 / Alexa 488 / Cy2 / Oregon Green |
| JOE / HEX / VIC | Alexa 532 / CAL Fluor Orange 560 / Bodipy 530/550 / TET / Yakima Yellow |
| Cy5 | ATTO 647N / ATTO 655 / LC 670 / DyLight 647 / Alexa Fluor 647 / TYE 705 |
| Cy3 | ATTO 565 / Alexa Fluor 555 / TYE 563 |
Download the datasheet, fill in with specifications (sequence, scale, purification, modifications), and attach it to your order. Confirm the PO number to proceed.
Place your order directly via our online ordering platform. Instant confirmation and estimated delivery window provided.
* The buttons above should point to the final .xlsx or .pdf file.
Checklist / Notas rápidas
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