RNAsure® is a specialized RNA stabilization reagent designed to preserve RNA in biological tissue samples immediately after collection. Because RNA molecules degrade rapidly due to endogenous RNases, fast and efficient stabilization is essential for reliable and high-quality downstream analysis. RNAsure® penetrates tissue and inhibits RNases on contact, preserving the integrity of RNA for applications such as RT-PCR, RNA sequencing, and gene expression analysis.
| Specifications | |
|---|---|
| Downstream application | Standard RNA isolation methods, as well as acid phenol extraction, or oligo(dT) selection of mRNA, RT PCR, RNA sequencing, gene expression analysis, array hybridisation |
| Recommended extraction kit | For RNA extraction we recommend using the InviTrap® Spin Universal RNA Mini Kit for animal tissue, or the InviTrap® Spin Plant RNA Mini Kit for plant tissue. |
| Stabilized nucleic acid | RNA |
| Starting material | Store animal tissues, plant tissues, cultured cells, bacteria in 5-10 times the sample volume, cut tissue into pieces with a diameter of ≤ 0.5 cm. |
| Storage/Stabilisation | Samples collected in RNAsure® can be stored/transported as follows without compromising RNA quality:
|
| Certification | RUO |
08 APR 2026
| Product Name | Package Size | Catalogue No. |
|---|---|---|
| RNAsure® | 100 ml 500 ml 1000 ml |
2010100100 2010100500 2010101000 |
RNA extraction from RNAsure® stabilized samples works with all standard methods, including commercial kits, acid phenol extraction, and oligo(dT) mRNA purification.
Before lysis, remove excess RNAsure® by gently tapping the sample on filter paper. Then homogenize according to your chosen extraction protocol.
For rigid or hard to lyse tissues, a Proteinase K pretreatment (1 mg/mL in TE, 10 min at 45 °C) can improve results. Use the entire lysis mix for extraction.
We recommend using the following RNA extraction kits:
Yes. RNAsure® can be used as a transport medium because it stabilizes the RNA in the collected sample during transport and storage. Once the sample is placed in RNAsure®, the RNA remains protected until you perform the extraction.
No. RNAsure® should not be used directly as input material for RNA extraction kits. Before starting any RNA isolation procedure, RNAsure® must be removed as completely as possible. A practical way to do this is to gently tap or blot the sample on filter paper to absorb any remaining stabilizer.
Once the excess RNAsure® is removed, continue with homogenization exactly as described in your extraction kit’s protocol.
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