Nucleic acid extraction is essential for molecular biology workflows, supporting applications like PCR, RT-PCR, and NGS. While automated systems are increasingly used, manual extraction kits remain important due to their cost-effectiveness, versatility across sample types, and hands-on control. Our manual kits combine advanced methods to ensure efficient and reliable DNA/RNA isolation tailored to your needs.
Non-chaotropic chemistry plays a key role in modern DNA/RNA extraction, preserving nucleic acid structure and allowing the use of enzymes like proteinases and lysozyme during the process. Unlike chaotropic agents (e.g., guanidine thiocyanate, SDS), which can degrade nucleic acids, non-chaotropic salts like ammonium sulphate offer gentler extraction. This results in high-quality DNA/RNA with minimal denaturation—ideal for sensitive downstream applications. Some of our kits use non-chaotropic reagents to improve yield and purity while protecting lytic enzymes.
Spin filter technology with silica membranes is a reliable method for DNA/RNA extraction. Under specific salt and pH conditions, nucleic acids bind to the membrane while impurities like proteins and salts can be effectively washed away. The huge surface area of the membrane ensures highest yields. Finally, the nucleic acids are released from the membrane using low-salt elution buffers or water, leaving high-pure nucelic acids. This technology is ideal for applications requiring high-purity DNA or RNA, such as qPCR, RT-PCR, and sequencing.
Highest Purity and Yield: Optimized for superior nucleic acid isolation
Broad Sample Compatibility: Kits for diverse starting materials
Certified Quality Standards: ISO 13485 certified CE-IVD and ISO 9001:2015 certified RUO kits.
Achieve high-quality extractions with InviSorb® spin filter kits, leveraging advanced spin filter technology for reliable nucleic acid purity. The InviSorb® product line utilizes spin filter technology to efficiently bind nucleic acids to silica surfaces through adsorption, enabling selective removal of impurities. By using gentle reagents, the integrity of the nucleic acids is preserved. This process ensures exceptionally pure DNA/RNA with outstanding yields, making it ideal for applications such as PCR, RT-PCR, and sequencing. Suitable for a wide range of starting materials, the InviSorb® product line provides flexibility for various needs. It is the optimal choice when requiring high-purity DNA or RNA. Trust InviSorb® for consistent, high-quality results in your nucleic acid extractions.
Purify RNA effortlessly with the InviTrap® product line, which employs a unique approach for the selective removal of DNA during RNA extraction, eliminating the need for DNase. The InviTrap® product line utilizes a unique approach for the selective removal of DNA during RNA extraction. During lysis, DNA binds to mineral carrier particles and is subsequently removed from the solution by centrifugation, without the need for DNases. This innovative method guarantees RNA that is almost free from DNA contamination, making it perfect for applications such as RT-PCR and RNA sequencing. Choose InviTrap® for reliable, pure RNA extractions that streamline your research.
Our PSP® (Preanalytical Sample Processing) product line offers seamlessly integrated sample collection, stabilization, and DNA extraction for preanalytical excellence. The PSP® Spin Stool DNA Basic Kit is engineered for the efficient processing of stool samples. This kit is optimized for use with our Stool Collection Tubes with DNA Stabilizer, ensuring the preservation of both microbial and host DNA for up to 3 months at room temperature. For saliva samples, the PSP® SalivaGene DNA Kit provides a robust solution. It is designed to perfectly work with our patented SalivaGene Swab Comfort (swab) and SalivaGene Collector (saliva) collection systems. These systems are designed to stabilize microbial and host DNA for 6 to 12 months at room temperature, facilitating reliable and reproducible genetic testing and microbiome analyses. Choose our PSP® products for cutting-edge solutions in preanalytical sample processing and DNA extraction.
Experience rapid and efficient DNA isolation with our InviPrep® Fast Lysis Buffer — no spin filters needed, just ultra-fast results. The InviPrep® Fast Lysis Buffer is designed for rapid and efficient lysis of cells without the need for spin filters, enabling ultra-fast DNA isolation. The buffer quickly breaks down cell walls and membranes, releasing DNA into the solution. The released DNA is immediately ready for PCR or sequencing, eliminating the need for time-consuming bind-wash-elute steps. This technology significantly reduces the overall extraction time, making it ideal for high-throughput applications.
Maximize convenience and efficiency with the RTP® product line, featuring lyophilized lysis components pre-portioned in individual tubes, ready for immediate use. The RTP® Pathogen Kit includes pre-filled extraction tubes with freeze-dried lysis components, enabling one-step sample lysis. This innovative approach saves hands-on time and reduces plastic waste by minimizing centrifugation and pipetting steps. Designed for versatility, the RTP® Pathogen Kit allows for the simultaneous isolation of viral DNA/RNA and bacterial DNA, making it an essential tool for comprehensive pathogen detection and analysis. Choose RTP® for streamlined, efficient sample preparation that meets the demands of modern research.
MSB® technology streamlines DNA fragment purification with a rapid two-step process, eliminating the need for washing steps. DNA binds to a silica membrane in the presence of minimal amounts of non-chaotropic salts, while impurities pass through, ensuring high-yield, pure DNA ready for use. Due to the minimal salt concentration no further washing steps are required. The MSB® Spin PCRapace kit efficiently purifies DNA from PCR reactions, cDNA synthesis, and ligation mixtures. For gel extractions, the InviSorb® Fragment CleanUp kit enables DNA recovery from agarose gels in TAE and TBE buffers. Together, these kits provide one of the fastest solutions for PCR product purification and gel extraction.
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